Association of African-American Students (AAAS)
AAAS was founded in 1968 to unify African American students on campus, promote unity among all students and faculty of the university, to motivate the community, members, and university to achieve higher social, educational, and economic status through service projects, cultural programming, and special events. AAAS currently has a diverse general body composed of more than 500 members, making it the largest organization under the OMSA umbrella and one of the largest student organizations at USC. The organization has a full-functioning executive board and seven committees including Freshmen Council, Cultural Awareness, Special Events, Community Service, Membership, Publicity, and Voices of Color, the organizations monthly newsletter.

BGLSA serves to provide information on support and social systems and networks for GLBT students and allies at the University of South Carolina, as well as to provide a forum for open discussion and positive interaction with the broader USC community in order to promote better awareness of bisexual, gay, lesbian and transgender students and allies.

Brothers of Nubian Descent (BOND) 
B.O.N.D is an informative discussion group, focusing on the trials and pressures facing black males today, not only on the USC campus, but in the state of South Carolina and the U.S. as well. The organization seek ways to improve all aspects of the lives of black men by a means of open communication through discussion, planning and execution. Our goal is to improve the success of black males here at USC while also serving the community and attracting more to apply and attend.  B.O.N.D. fosters and supports intellectual dialogue by creating a cultural support group.

Chosen Gospel Ensemble
Created to provide cultural inspiration at campus events, Chosen sings music that has come out of the African-American worship experience. 

National Association for the Advancement of Colored People (NAACP)
The purpose of NAACP is to provide a medium for the exchange of ideas to confront issues that face the community and work toward solutions to solve those issues. By educating students, facilitating meetings, and
other special events, NAACP strives to make a difference at USC. 

The purpose of SAVVY is to provide assistance to multicultural female students looking for a way to maximize their chances at self-improvement and enhance their abilities during their affiliation here at USC.

Student Association for Latin American (SALA)
The first student organization recognized for Latino students, SALAs purpose is to promote cultural awareness with regard to Latin American issues, countries, and people, on-campus, both inside and outside of the classroom.